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OpportunitySTRATEGIC IEC/ COMMUNICATION PLANstrategic framework for targeted IEC activities encompassing mass media, along with mid-media and inter-personal activities so as to disseminate information about the various health schemes in the masses. The year-long IEC/Communication Plan had month-wise focus on health days and health themes. While some activities were taken up to coincide with ‘Health Days’, others were week and month long plans for focussed multi-media campaigns on schemes of the Ministry. These centered around topics such as Integrated Diarrhoea Control Fortnight (IDCF), Breastfeeding Week, Tobacco Control etc. Seasonal ailments such as Dengue, H1N1 etc., needed campaigns for a longer time The objective is also to encourage build-up of health seeking behaviour among the masses in keeping with the focus on promotive and preventive health. The IEC strategy has catered to the different needs of the rural and urban masses through the various tools used for communicationBy: rupaliThursday, May 27, 2021WATER, ENERGY, AND THE ENVIRONMENT+1
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PostNatural resources are resources that exist without any actions of humankind. This includes the sources of valued characteristics such as commercial and industrial use, aesthetic value, scientific interest and cultural value. On Earth, it includes sunlight, atmosphere, water, land, all minerals along with all vegetation, and animal life.By: rupaliTuesday, May 25, 2021AGRI-FOOD SYSTEMS+1
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PostThe Information, Education & Communication (IEC) strategy aims to create awareness and disseminate information regarding the benefits available under various schemes/programmes of the Ministry and to guide the citizens on how to access them. The objective is also to encourage build-up of health seeking behaviour among the masses in keeping with the focus on promotive and preventive health. The IEC strategy has catered to the different needs of the rural and urban masses through the various tools used for communication.By: rupaliTuesday, May 25, 2021YOUTH EMPOWERMENT+1
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ArticleFunctional genomics and the biosynthesis of artemisininArtemisinin, a sesquiterpene lactone endoperoxide derived from the glandular secretory trichomes (GSTs) of Artemisia annua, provides the basis for the most effective treatments of malaria. The biology and biochemistry of GSTs of the Asteraceae and their biosynthesis of isoprenoids is reviewed. Recent efforts to understand the biosynthesis of artemisinin in A. annua GSTs are discussed in detail. This includes the development in the authors’ laboratory of an expressed sequence tag (EST) approach to identifying the relevant biosynthetic genes using isolated GST as a source of mRNA. This has lead to the isolation of a cDNA encoding CYP71AV1, a multifunctional cytochrome P450 which catalyzes multiple oxidations of the sesquiterpene intermediate amorpha-4,11-diene to artemisinic acid. Further biochemical and molecular genetic work is required to elucidate the precise route from artemisinic alcohol to artemisinin and to engineer more efficient low cost production of artemisinin-based antimalarial drugs.By: rupaliThursday, May 27, 2021WATER, ENERGY, AND THE ENVIRONMENT+1
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ArticleNatural product substancesNatural product substances have historically served as the most significant source of new leads for pharmaceutical development. However, with the advent of robotics, bioinformatics, high throughput screening (HTS), molecular biology-biotechnology, combinatorial chemistry, in silico (molecular modeling), and other methodologies, the pharmaceutical industry has largely moved away from plant-derived natural products as a source for leads and prospective drug candidates. Can, or will, natural products ever recapture the preeminent position they once held as a foundation for drug discovery and development? The challenges associated with the development of natural products as pharmaceuticals are illustrated by the Taxol® story. Several misconceptions, which constrain the utilization of plant natural products, for the discovery and development of pharmaceuticals, are addressed to return natural products to the forefront. have historically served as the most significant source of new leads for pharmaceutical development. However, with the advent of robotics, bioinformatics, high throughput screening (HTS), molecular biology-biotechnology, combinatorial chemistry, in silico (molecular modeling), and other methodologies, the pharmaceutical industry has largely moved away from plant-derived natural products as a source for leads and prospective drug candidates. Can, or will, natural products ever recapture the preeminent position they once held as a foundation for drug discovery and development? The challenges associated with development of natural products as pharmaceuticals are illustrated by the Taxol® story. Several misconceptions, which constrain utilization of plant natural products, for discovery and development of pharmaceuticals, are addressed to return natural products to the forefront.By: Vijaya Super adminTuesday, May 25, 2021AGRI-FOOD SYSTEMS+1
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PostMesenchymal stem cells (MSCs) are adult, immunomodulatory stem cells which reside in almost all postnatal tissues. Viral antigens and damage-associated molecular patterns released from injured and infected cells activate MSCs, which elicit strong antiviral immune response.By: rupaliMonday, May 24, 2021AGRI-FOOD SYSTEMS
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OpportunityNatural plant productsNatural plant products have been used throughout human history forvarious purposes. Having co-evolved with animal life, many of the plants fromwhich these natural products are derived are billions of years old. Tens ofthousands of these products are produced and discovered since. Dyes areone of them. Fabric dye has been one of the common things used in these moderndays. But using it has also disadvantages to the environment. Therun-offfrom fabric dye pollutes water ways, and the dyes themselves are not sohealthy for workers who are around them day in and day out, either.There areways to prevent these harmful effects of using dye to both the environmentand human beings, and that is by using organic substances instead ofcommercialized products which utilizes toxic ingredients.By: rupaliWednesday, Jun 9, 2021AGRI-FOOD SYSTEMS+1
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