Additional content that appears and disappears in coordination with keyboard focus or pointer hover often leads to accessibility issues. Reasons for such issues include:

the user may not have intended to trigger the interaction
the user may not know new content has appeared
the new content may intefere with a user's ability to do a task
Examples of such interactions can include custom tooltips, sub-menus and other nonmodal popups which display on hover and focus. The intent of this success criterion is to ensure that authors who cause additional content to appear and disappear in this manner must design the interaction in such a way that users can:

perceive the additional content AND
dismiss it without disrupting their page experience.
There are usually more predictable and accessible means of adding content to the page, which authors are recommended to employ. If an author does choose to make additional content appear and disappear in coordination with hover and keyboard focus, this success criterion specifies three conditions that must be met:

dismissable
hoverable
persistent
Each of these is discussed in a separate section.

The production chain with natural products has three major parts to consider. The
fi rst is agricultural, followed by, for example, extraction to get a concentrated
raw extract, and in pharmaceutical applications (not with cosmetics and nutraceuticals) a fi nal purifi cation step is necessary in order to get an ultrapure product.
All the steps combined contribute to the overall yield and determine the fi nal
economics.
To highlight the importance of including the complete production chain, we
can consider growing a crop of plants containing oleanoic acid. This is found in
several plants (almond hulls, privet, rosemary, thyme, clove, lavender, olive, hawthorn, periwinkle etc.) with a content less than 1% in dry mass. Higher values
were observed only with a different kind of sage. The value varies with location
and local climate (e.g., Germany versus Greece), types of soil (sandy, thus irrigation needed), distance between the growing rows and cultivar. With the latter,
higher content is with plants from scions obtained through vegetative reproduction ( Salvia offi cinalis ) compared with those from sowing ( S. lavendulifolia ).
However, planting with scions is very labor - intensive, which has quite an impact
in respect to labor costs, and sowing is then the alternative. Optimal conditions
for sage are with warm and wind - protected sites, with a light soil containing
compost and water. Dry periods are no major problem and the plants should
grow in rows (distance 25 – 50 cm) as depicted in Figure 1.7 [15] . Usually, the
useful life is four to fi ve years and for soil recovery a four - year interval is recommended. If the plants are used to gain pharmaceutical extracts, all cultivation steps
(sowing, manuring etc.) must be documented and with pest management any
pesticide (date, dosage etc.) must be registered. With sage the use of herbicides is
forbidden and two cuts per year are recommended. After air classifi cation the
leaves are dried and according to the Deutsches Arzneibuch only 2% impurities are

The production chain with natural products has three major parts to consider. The
fi rst is agricultural, followed by, for example, extraction to get a concentrated
raw extract, and in pharmaceutical applications (not with cosmetics and nutraceuticals) a fi nal purifi cation step is necessary in order to get an ultrapure product
To highlight the importance of including the complete production chain, we
can consider growing a crop of plants containing oleanoic acid. This is found in
several plants (almond hulls, privet, rosemary, thyme, clove, lavender, olive, hawthorn, periwinkle etc.) with a content less than 1% in dry mass. Higher values
were observed only with a different kind of sage. The value varies with location
and local climate (e.g., Germany versus Greece), types of soil (sandy, thus irrigation needed), distance between the growing rows and cultivar. With the latter,
higher content is with plants from scions obtained through vegetative reproduction ( Salvia offi cinalis ) compared with those from sowing ( S. lavendulifolia ).
However, planting with scions is very labor - intensive, which has quite an impact
in respect to labor costs, and sowing is then the alternative. Optimal conditions
for sage are with warm and wind - protected sites, with a light soil containing
compost and water. Dry periods are no major problem and the plants should
grow in rows (distance 25 – 50 cm) as depicted in Figure 1.7 [15] . Usually, the
useful life is four to fi ve years and for soil recovery a four - year interval is recommended. If the plants are used to gain pharmaceutical extracts, all cultivation steps
(sowing, manuring etc.) must be documented and with pest management any
pesticide (date, dosage etc.) must be registered. With sage the use of herbicides is
forbidden and two cuts per year are recommended