A new permanently positively charged stable isotope labeling (SIL) agent pair, 4-(((2,5-dioxopyrrolidin-1-yl)oxy)carbonyl)-N,N,N-trimethylbenzenaminium iodide(DPTBA) and its deuterated counterpart d3-DPTBA,    Read more

A new permanently positively charged stable isotope labeling (SIL) agent pair, 4-(((2,5-dioxopyrrolidin-1-yl)oxy)carbonyl)-N,N,N-trimethylbenzenaminium iodide(DPTBA) and its deuterated counterpart d3-DPTBA,  Read more

A new permanently positively charged stable isotope labeling (SIL) agent pair, 4-(((2,5-dioxopyrrolidin-1-yl)oxy)carbonyl)-N,N,N-trimethylbenzenaminium iodide(DPTBA) and its deuterated counterpart d3-DPTBA,  Read more

A new permanently positively charged stable isotope labeling (SIL) agent pair, 4-(((2,5-dioxopyrrolidin-1-yl)oxy)carbonyl)-N,N,N-trimethylbenzenaminium iodide(DPTBA) and its deuterated counterpart d3-DPTBA,  Read more

Abstract A new permanently positively charged stable isotope labeling (SIL) agent pair, 4-(((2,5-dioxopyrrolidin-1-yl)oxy)carbonyl)-N,N,N-trimethylbenzenaminium iodide(DPTBA) and its deuterated counterpart d3-DPTBA, was designed and synthesized. The SIL agents were applied to the liquid chromatography–tandem mass spectrometry analysis of alkylphenols. Light labeled standards and heavy labeled samples were mixed and analyzed simultaneously. Matrix effect which mainly occurred during the ionization process was minimized because of the identical ionization processes between samples and standards. Meanwhile, derivatization made alkylphenols be positively charged, and thus the sensitivity was enhanced. The limits of detection were in the range of 1.5–1.8 ng/L, and the limits of quantitation were in the range of 4.8–6.1 ng/L. The developed method was applied to analyze alkylphenols migrated from plastics to edible oils. The recoveries for all analytes were in the range of 88.6–95.3%, while the matrix effects for all analytes were in the range of 96.2–99.6%. Read more

The onion, known as the bulb onion or common onion, is not only a key ingredient in many tasty and healthy vegetarian meals but also many traditional medicines. Nine new flavonoids [cepaflavas A, B (5, 6), cepadials A–D (7–9 and 14), and cepabiflas A–C (10–12)] and six known compounds (1–4, 13, 15) were obtained from the outer skins of Allium cepa L. Among them, compounds 5, 6, and 9 might be artificial products formed during extraction and isolation. New compounds were structurally elucidated using various spectroscopy/spectrometry techniques, including NMR and HRMS, and computational methods. T Read more

Agriculture is the science and art of cultivating plants and livestock. Agriculture was the key ... The major agricultural products can be broadly grouped into foods, fibers, fuels and raw materials (such as rubber). Food classes include cereals ... Read more

Most cities and towns everywhere have local business groups that meet on a regular basis. In North America the largest business group is the Chamber of Commerce. The U.S. Chamber of Commerce was formed in 1912 and the Canadian CoC soon afterwards, in 1925. According to the Canadian Chamber of Commerce website, the CoC's primary mandate is to "advocate for public policies that will foster a strong, competitive economic environment that benefits businesses, communities and families".  Read more

Wild harvesting mushrooms can also be a lot of fun, and fairly lucrative, if you know where to go and when, and can find a buyer. Many gourmet restaurants are thrilled to get wild-harvested mushrooms, so it’s worth trying to make these connections. I have done this with both morel’s and hen of the woods (see pictures below). But make sure you know what you’re doing if you’re going to hunt (for more information see below). Also anyone interested in this topic should check out Read more

Technologies. People often ask, what exactly do you mean by “breakthrough”? It’s a reasonable question—some of our picks haven’t yet reached widespread use, while others may be on the cusp of becoming commercially available. What we’re really looking for is a technology, or perhaps even a collection of technologies, that will have a profound effect on our lives. For this year, a new technique in artificial intelligence called GANs is giving machines imagination; artificial embryos, despite some thorny ethical constraints, are redefining how life can be created and are opening a research window into the early moments of a human life; and a pilot plant in the heart of Texas’s petrochemical industry is attempting to create completely clean power from natural gas—probably a major energy source for the foreseeable future. These and the rest of our list will be worth keeping an eye on. Read more

Business networking is the process of establishing a mutually beneficial relationship with other business people and potential clients and/or customers   The primary purpose of business networking is to tell others about your business and hopefully turn them into customers. Read more

Meeting people in person seems old fashioned in the digital age, but wherever possible you should network face-to-face. Social media platforms such as Facebook, LinkedIn, and Twitter are excellent ways to communicate with customers and business associates, but they do not substitute for meeting people in person. A lot of local business is still done on a handshake basis, and the best way to network with other local business owners and entrepreneurs is through business groups.   The best business networking groups operate as exchanges of business information, ideas, and support. The most important skill for effective business networking is listening; focusing on how you can help the person you are listening to rather than on how he or she can help you is the first step to establishing a mutually beneficial relationship. Read more